Zelapar (Selegiline hydrochloride) is a prescription medication used with carbidopa or levodopa to treat movement disorders caused by Parkinson's disease. Parkinson's disease is a brain disorder that causes uncontrollable or unintended movements like shaking, stiffness, balance, and coordination difficulties. Zelapar prevents dopamine's breakdown, improving tremors, muscle stiffness, and sudden switches between normal movement and stiffness. This medication may also improve the range of motion and ability to exercise, dress, and walk. However, Zelapar is not a cure for Parkinson's disease. The active ingredient in Zelapar is Selegiline hydrochloride. Selegiline hydrochloride belongs to a class of drugs called monoamine oxidase type B (MAO-B) inhibitors. It works by increasing the amount of dopamine in the brain. Dopamine is a natural substance that controls movement in the body.
Manufacturer Information
We currently offer the brand Zelapar from the United Kingdom, manufactured by Cephalon and Teva in the strength of 1.25mg tablets. The generic Selegiline hydrochloride is not available.
Get medical help immediately if you have any of these signs or an allergic reaction while using Zelapar. The most common side effects of Zelapar may include the following:
• Constipation;
• Dizziness;
• Insomnia;
• Mouth sores or ulcers;
• Nausea;
• Skin rash;
• Stomach pain;
• Swallowing difficulties
Contact your doctor right away if you have any of the severe side effects, including:
• Blurred vision;
• Breathing difficulties;
• Confusion;
• Dangerously high blood pressure;
• Hallucinations;
• Increased tremors or uncontrolled muscle movements;
• Light-headedness;
• Severe chest pain
These are not all the side effects of Zelapar. Always contact your doctor if you notice any unusual symptoms.
You should not use Zelapar if you are allergic to Selegiline hydrochloride or any ingredient in Zelapar. Before you start using this medication, tell your doctor about your medical history, especially if you:
• Are breastfeeding or plan to breastfeed;
• Are pregnant or plan to become pregnant;
• Have high blood pressure;
• Have kidney disease;
• Have liver disease;
• Have phenylketonuria
Tell your doctor about all your medications, including prescription, OTC, herbal supplements, and vitamins. There may be drug interactions between Zelapar and cough medicines containing dextromethorphan, tramadol, cyclobenzaprine, methadone, or St. John's wort. Avoid Zelapar with citalopram, venlafaxine, phenelzine, methylene blue injection, etc. Do not use Zelapar if you have taken fluoxetine, Prozac, or Serafim within the past five weeks. Tell your doctor if you are pregnant or planning to become pregnant. It is unknown if Zelapar will harm an unborn baby. It is not known if Selegiline is excreted in breast milk. Inform your doctor if you are breastfeeding or planning to breastfeed. Take Zelapar precisely as prescribed by your doctor. Your doctor may occasionally change your dose. Do not change doses or medication schedules without consulting your doctor. Do not swallow Zelapar orally disintegrating tablet. Place it under your tongue and allow it to dissolve in your mouth without chewing. Swallow several times as the tablet dissolves. Do not eat or drink anything for at least 5 minutes after taking Zelapar orally disintegrating tablet. Avoid eating foods high in thiamine like soybeans, soy sauce, yeast extracts, aged cheeses, sausages, air-dried meats, or beer from a tap while taking Zelapar and for 14 days after you stop. This medication may impair your thinking. You may fall asleep suddenly during normal daytime activities. Avoid driving or any activity that requires you to be alert. Store Zelapar at room temperature, away from moisture and heat.
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