Vetoryl (Trilostane) is a prescription medication used to treat pituitary-dependent and adrenal-dependent hyperadrenocorticism (Cushing’s disease or syndrome) in dogs. Hyperadrenocorticism occurs when the pet’s adrenal glands produce too much cortisol. Characteristic signs of this disease include frequent urination, excessive drinking, pot belly, thin skin, hair loss, excessive panting, and lethargy. Vetoryl is not a cure for Cushing’s disease, but it helps manage it and improve your pet’s quality of life. The active ingredient in Vetoryl is Trilostane. Trilostane belongs to a class of drugs called steroidogenesis inhibitors. It inhibits the production of cortisol in the adrenal cortex.
Manufacturer Information
We currently offer the brand Vetoryl from the United Kingdom in the strength of 10 mg, 30 mg, and 60 mg capsules. The generic Trilostane is not available.
Get medical help immediately if your pet has any of these signs or an allergic reaction while taking Vetoryl. The most common side effects of Vetoryl may include the following:
• Vomiting;
• Lethargy;
• Appetite loss;
• Diarrhea
Contact your doctor right away if your pet has any of the severe side effects, including:
• Collapse;
• Bloody diarrhea;
• Symptoms of an allergic reaction, including breathing difficulties, profuse salivation, swollen lips, face, or airways
These are not all of the side effects of Vetoryl. Always contact your veterinary doctor if you notice any unusual symptoms.
Your pet should not take Vetoryl if they are allergic to Trilostane or any ingredient in Vetoryl. Before you give your pet this medication, tell your doctor about their medical history, especially if they:
• Are pregnant;
• Have kidney or liver disease;
• Have primary hepatic disease;
• Have renal insufficiency
Tell your doctor about all your medications, including prescription, OTC, herbal supplements, and vitamins. There may be drug interactions between Vetoryl and other medicines, including potassium-sparing diuretics like spironolactone. Tell your veterinarian if your dog is pregnant. Taking Vetoryl in pregnancy may result in early pregnancy loss. Inform your veterinary doctor if your dog is breastfeeding. The effect of Trilostane in lactating dogs is unknown. Use Vetoryl precisely as prescribed by your veterinary doctor. The dosage depends on the weight of your dog. Administer the capsules with food. Do not open or split the capsules. Wash your hands with soap and water after administration to avoid exposure to the drug. This drug is for use in dogs only. It is not for human use. If you are pregnant or planning to become pregnant, wear gloves when handling Vetoryl. Keep this medicine and other medicines away from children. Store at controlled room temperature of 250C (770F).