Steglujan (Ertugliflozin/Sitagliptin) is a prescription medication used in combination with diet and exercise to control blood sugar in adults with type 2 diabetes mellitus. In type 2 diabetes, the pancreas does not produce enough insulin. Consequently, the cells respond poorly and take in less sugar. The active ingredients in Steglujan are Ertugliflozin and Sitagliptin. Ertugliflozin belongs to a class of drugs called sodium-glucose co-transporter 2 (SGLT2) inhibitors. It works by helping the kidneys get rid of glucose from the bloodstream. Sitagliptin belongs to a class of drugs called dipeptidyl peptidase-4 (DPP-4) inhibitors. It works by regulating the levels of insulin your body produces after eating. Steglujan will only work for type 2 diabetes. The drug is not for treating type 1 diabetes.
Manufacturer Information
We currently offer the brand Steglujan from Australia manufactured by MSD in the strength of 5mg/100mg tablets. The generic Ertugliflozin/Sitagliptin is not available.
Get medical help immediately if you have any of these signs or an allergic reaction while using Steglujan. The most common side effects of Steglujan may include the following:
• Frequent urination;
• Headache;
• Upset stomach
Contact your doctor right away if you have any of the severe side effects, including:
• Signs of a bladder infection, such as pain or burning when you urinate, increased urination, bloody urination, pain in your pelvis or back;
• Signs of dehydration such as dizziness, light-headedness, weakness;
• Symptoms of pancreatitis such as severe pain in your upper stomach spreading to your back with or without nausea and vomiting
These are not all of the side effects of Steglujan. Always contact your doctor if you notice any unusual symptoms.
You should not use Steglujan if you are allergic to Ertugliflozin, Sitagliptin, or any ingredient in Steglujan. Before you start using this medication, tell your doctor about your medical history, especially if you:
• Are breastfeeding or planning to breastfeed;
• Are pregnant or planning to be pregnant;
• Have a bladder infection or urination problems;
• Have a diabetic foot ulcer or amputation;
• Have blood circulation problems, especially in your legs;
• Have ever had diabetic ketoacidosis;
• Have a heart failure such as heart failure;
• Have gallstones;
• Have high triglycerides;
• Have severe kidney problems
Tell your doctor about all your medications, including prescription, OTC, herbal supplements, and vitamins. There may be drug interactions between Steglujan and other medicines, like metoprolol, amiodarone, carbamazepine, cyclosporine, digoxin, mefloquine, mifepristone, etc. Tell your doctor if you are pregnant or planning to become pregnant. It is not known whether Steglujan will harm an unborn baby. Pregnancy may cause or worsen diabetes. Your doctor will prescribe appropriate diabetes treatment during pregnancy. Inform your doctor if you are breastfeeding or planning to breastfeed. It is unknown if Ertugliflozinor Sitagliptin passes into breast milk or if it may affect a nursing infant. Use this medicine exactly as your doctor prescribes. Steglujan is a tablet. Take the tablet once per day. You may take Steglujan with or without food. Your blood sugar will need to be tested often to check the level of ketones in your urine. This drug may cause low blood sugar. Eat a fast-acting source of sugar like fruit juice, crackers, raisins, or non-diet soda if you feel hungry, dizzy, irritable, or anxious. Your doctor may prescribe a glucagon injection kit for severe low blood sugar. This drug may cause dizziness. Avoid getting up too fast from a lying or sitting position. Do not drink alcohol when using Steglujan. Alcohol may increase the side effects of the drug. Store at room temperature, away from moisture and heat. Keep out of the sight and reach of children.