Oxsoralen (Methoxsalen) is a prescription medication used with ultraviolet light A (UVA) to treat severe skin conditions, including psoriasis, eczema, vitiligo, and some cutaneous lymphomas (a type of cancer that affects the skin and blood and sometimes the lymph nodes and other organs). Psoriasis is a type of skin disorder characterized by thick, itchy patches, silvery scales, and erythematous skin. The active ingredient in Oxsoralen is Methoxsalen. Methoxsalen belongs to the class of medication called Psoralen, topical antipsoriatic. It increases the skin's sensitivity to ultraviolet light and reduces cancer cell growth. Oxsoralen is not recommended for use in children below 12 years of age. Oxsoralen may be used for other conditions not mentioned in this guide, depending on your doctor's decision.

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Get medical help immediately if you have any of these signs of an allergic reaction while taking Oxsoralen. The most common side effects of Oxsoralen may include:
• Changes in skin color;
• Extension of psoriasis;
• Headache;
• Insomnia;
• Mild itching;
• Nausea and vomiting;
• Rash

Contact your doctor right away if you have any of the severe side effects, including:
• Blurred vision;
• Skin burns;
• Wrinkling skin;
• Worsening of skin condition

You should not take Oxsoralen if you are allergic to Methoxsalen or have other allergies. Before you start taking this medication, tell your doctor about your medical history, especially if you:
• Are breastfeeding or plan to breastfeed;
• Are pregnant or plan to become pregnant;
• Have blood disorders such as porphyria;
• Have intestinal problems;
• Have liver problems;
• Have lung or breathing problems;
• Have skin cancer, including melanoma and squamous cell carcinoma

Tell your doctor immediately if you become pregnant or think you may be pregnant. Do not go for ultraviolet light treatment during pregnancy. Methoxsalen may harm an unborn baby. It is unknown if this medication passes into breast milk. Because of the possible risk to the infant, breastfeeding while using this drug is not recommended. Consult your doctor before breastfeeding. Oxsoralen is a tablet and should be taken with a cup of water. You should take it with food to hasten its absorption. You should take it a few hours before having the Ultraviolet light treatment or as your doctor directs. Do not take more than your prescribed dose. Your dose depends on your condition's severity and response to treatment. Depending on your doctor, you may visit the clinic for treatment for at least two to four weeks. You should not miss your appointment. Reach out to your doctor if you develop a serious side effect, such as severe itching and redness of the skin. You should avoid excessive exposure to sunlight a few hours after ultraviolet light treatment. Consult your doctor if there is no improvement in your condition or it worsens. Tell your doctor about all your medications, including prescription, OTC, herbal supplements, and vitamins. There may be a drug interaction between Methoxsalen and other medications, such as phenytoin and tegafur. It is unknown if Oxsoralen is safe and effective in children. Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing. Keep out of the reach of children.

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