Nozinan (Methotrimeprazine) contains the active ingredient Methotrimeprazine which belongs to the class of medications called phenothiazines. Nozinan is used to treat psychotic disturbances, such as acute and chronic schizophrenia, psychosis in the elderly, and manic depressive syndromes. It can also be used in conditions associated with anxiety and tension, as a pain reliever (for certain types of pain), as a sedative, and for nausea and vomiting caused by certain conditions or for the management of insomnia. Nozinan helps to reduce and control psychotic symptoms, tranquilize, induce sleep, and relieve pain. You should remain lying down for at least one hour after your injection, because you may experience a decrease in blood pressure. You may experience side effects if the drug is stopped suddenly. Contact your physician before stopping your drug.

Manufacturer Information

Canadian Pharmacy King currently offers the brand Nozinan Ampoules for Injection from Canada manufactured by Sanofi Aventis. The generic Methotrimeprazine tablets come from Canada by a different manufacturer. Brand Nozinan is available in the strength of 25 mg/ml/1 ml. Generic equivalent of Nozinan (Methotrimeprazine) is available in the strength of 2 mg, 5 mg, 25 mg, and 50 mg tablets.

The common side effects of Nozinan may include drowsiness, dryness of the mouth, constipation and difficulty urinating. Contact your doctor right away if you have any of the following symptoms:

• Allergic reactions, such as skin rash, redness or itching, soreness of the mouth, gums or throat;
• Low blood pressure with symptoms such as feeling dizzy, especially when getting up from a lying or sitting position;
• Rapid or irregular heartbeat

This is not a complete list of side effects and others may occur. Please call your doctor if you have any further concerns or questions.

Nozinan is not indicated in elderly patients with dementia and is not recommended for use in patients with Parkinson’s Disease. If you experience severe constipation and you are elderly, please consult your doctor as soon as possible. Avoid consuming alcoholic beverages while on Nozinan therapy. Do not take Nozinan if you are allergic to Nozinan, to phenothiazines, are in an altered state of consciousness, are going to receive anesthesia in the spine, are at risk for urinary retention; are at risk of having glaucoma, are taking dopaminergics, have liver disease, a blood disorder, had brain damage or have severely low blood pressure, have a tumor of the adrenal gland, severe heart or blood vessel disorder, low level of neutrocytes in your blood. Before taking Nozinan, inform your doctor if you are pregnant or breast-feeding, have heart or blood vessel disease, have a history of cerebrovascular disease including strokes, have or have had epilepsy, have severe kidney problems. Tell your doctor, nurse, or pharmacist about all the medicines you take, including drugs prescribed by other doctors, vitamins, minerals, natural supplements, or alternative medicines. Drugs that may interact with Nozinan include: allergy pills, sleeping pills, pain killers, medications for seizure, anti-depressant pills, medications for mental illness, Dopaminergics to treat Parkinson’s Disease, drugs that prolong the QT interval, water pills, amphotericin B, corticosteroids and laxatives, drugs metabolized by the CYP2D6 enzyme system (including codeine, venlafaxine, amitriptyline and nortriptyline), drugs that lower blood pressure, guanethidine, atropine and atropine-like substances, lithium.

Check out our Blog Post

Over 40? 11 Important Health Signs to Watch For