Maxzide is a combination medication containing triamterene (potassium-sparing diuretic) and hydrochlorothiazide (thiazide diuretic). Maxzide (Triamterene/HCTZ) is used to treat fluid retention and high blood pressure and typically given to people who have gotten hypokalemia (low potassium levels in the blood) from other diuretics. It works by preventing your body from absorbing too much salt and keeping potassium levels from getting too low. The usual recommended start dose is 50 mg/25 mg.

Manufacturer Information

Get medical help immediately if you have any of these signs of an allergic reaction while taking Triamterene/HCTZ.

• Difficulty breathing;
• Hives;
• Swelling of your face, lips, tongue or throat

Stop taking Maxzide and call your doctor at once if you have one of these serious side effects:

• Blurred or tunnel vision, eye pain, seeing halos around lights;
• Lightheadedness;
• Fast, slow or uneven heart rate;
• Dark urine, clay-colored stools,
• Jaundice;
• Severe pain in your upper stomach spreading to your back;
• Nausea and vomiting;
• Fever, sore throat, headache with severe blistering, peeling, and red skin rash;
• High potassium levels in the blood;
• Other electrolyte imbalances;
• Kidney problems;
• Lupus-like syndrome

Less serious side effects of Triamterene/HCTZ may include stomach, nausea, diarrhea, constipation, dizziness, headache, blurred vision, or dry mouth.

This is not a complete list of side effects and others may occur. Please call your doctor if you have any further concerns or questions.

Maxzide should be taken as prescribed by your doctor. Talk to your doctor about your medical history to be sure you can safely take Maxzide. Particularly if you have a history of diabetes, cirrhosis or other liver disease, gout, if you’re on a low-salt diet, history of cataracts or glaucoma, history of kidney stones, or an allergy to sulfa drugs or penicillin. Do not use this medication if you have kidney disease, high potassium levels in the blood, if you’re on other diuretics or taking potassium supplements (unless advised to by your doctor). It is not known how this medication will harm an unborn baby. Maxzide can pass into breastmilk it is not advised you breastfeed while taking this medication. There may be an interaction between Maxzide and other medications such as any other blood pressure medication, blood thinners, oral diabetes medications, steroid medications, ACE inhibitors, NSAIDs, laxatives, and more. If you are taking any of these medications, speak to your doctor.