Lodoco (Colchicine Extended Release) is an anti-inflammatory medication used to prevent recurrent gout attacks. Gout is a condition in which there is too much uric acid in the blood, and it usually causes pain across joints, such as the knee, big toe, and ankle joints. Colchicine is also used to reduce the risk of myocardial infarction (MI), stroke, coronary artery diseases and cardiac death in adults diagnosed with atherosclerotic disease or at risk for cardiovascular diseases. The active ingredient in Lodoco is Colchicine. Colchicine belongs to the group of medications called antigout agents. Colchicine works by decreasing swelling and lessening the buildup of uric acid crystals that cause pain in the affected joint(s).
Manufacturer Information
We currently offer the brand Lodoco from Canada also called Myinfla manufactured by Pendopharm Pharmascience in the strength of 0.5 mg tablet only. The generic Colchicine Extended Release is not available.
Get medical help immediately if you have any of these signs or an allergic reaction while using Lodoco. The most common side effects of Lodoco may include the following:
• Abdominal Pain;
• Diarrhea;
• Cramping;
• Muscle pain;
• Nausea;
• Vomiting
Contact your doctor right away if you have any of the severe side effects, including:
• Continuous tingling sensation in your fingers and toes;
• Passage of dark colour urine;
• Numbness of hands, feet, arms, and legs;
• Severe muscle weakness or pain
These are not all the side effects of Lodoco. Always contact your doctor if you notice any unusual symptoms.
Before taking Colchicine, tell your doctor or pharmacist if you are allergic to it or have any other allergies. Also, inform your doctor if you are currently taking CYP3A4 inhibitors or P-glycoprotein inhibitors. Concurrent use of strong CYP3A4 inhibitors (such as ritonavir, indinavir, and clarithromycin) with Lodoco may be harmful.
Before you start using this medication, tell your doctor about your medical history, especially if you:
• Are breastfeeding or planning to breastfeed;
• Are pregnant or planning to be pregnant;
• Have blood clotting disorders;
• Have diabetes mellitus;
• Have liver problems;
• Have severe kidney diseases
Tell your doctor about all your medications, including prescription, OTC, herbal supplements, and vitamins. There may be drug interactions between Lodoco and other medicines, especially other topical medications. Tell your doctor if you are pregnant, plan to become pregnant, or breastfeeding a child. During pregnancy, this medication should be used only when needed. Your doctor will discuss the risks and benefits of using Lodoco as a pregnant woman. Colchicine passes into breast milk. It would be best to consult your doctor before breastfeeding. Your doctor may recommend that you separate the time(s) you take your medication from the times you breastfeed. Lodoco is a tablet that should be taken orally with a cup of water with or without food. It is recommended to take a tablet (0.5 mg) daily. Do not double your dose, as this may worsen your condition. Follow your prescription label carefully. It would be best to know that Colchicine is not a pain medication. Do not use it to relieve other causes of pain. Alcohol can make this drug work less well. Limit alcohol intake while taking this drug. Avoid taking grapefruit or grapefruit juice when treating gout with Lodoco.
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