Lodalis (Colesevelam) is a medication used along with a proper diet and exercise to lower cholesterol in people with high cholesterol levels in the blood, and is also used to lower high blood sugar levels in people with type 2 diabetes mellitus. Lowering cholesterol can prevent heart disease, strokes, and heart attacks. Lowering high blood sugar levels can prevent kidney damage, blindness, nerve problems, loss of limbs, and sexual function problems. Lodalis belongs to a class of drugs called acid-binding resins. It works by removing bile acid from the body. This causes the liver to make more bile acid by using cholesterol, which reduces cholesterol levels in the blood.

Manufacturer Information

Seek emergency medical help if you have any signs of an allergic reaction to this medication. The common side effects of Lodalis may include constipation, nausea, and upset stomach.

Stop taking Lodalis and call your doctor immediately if you have:
• Pancreatitis;
• Severe constipation;
• Severe stomach pain

This is not a complete list of side effects and others may occur. Please call your doctor if you have any further concerns or questions.

You should not take Lodalis if you are allergic to Colesevelam or if you have:
• A history of bowel obstruction;
• A history of pancreatitis caused by high triglycerides;
• Diabetic ketoacidosis;
• Very high levels of triglycerides in your blood

Prior to taking this medication, tell your doctor if you have ever had:
• A vitamin A, D, E, or K deficiency;
• Blockage in your digestive tract;
• Slow digestion;
• Surgery on your stomach or intestines;
• Trouble swallowing

Avoid eating foods high in fat or cholesterol. Tell your doctor about all the medications you take including prescription, nonprescription, herbal products, and vitamins. There may be a drug interaction between Lodalis and other medications. Consult your doctor if you are pregnant or breastfeeding. Lodalis should not be used in girls who have not yet started having menstrual periods and to children younger than 10 years old.

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