Locoid (Hydrocortisone Butyrate) is a topical prescription medication used to relieve swelling, itching and redness associated with various inflammatory skin conditions such as psoriasis, dermatitis, eczema, and allergies. The active ingredient in Locoid cream is Hydrocortisone Butyrate. Hydrocortisone belongs to the group of medications called topical corticosteroids. It works by preventing the release of destructive acid hydrolases from leukocytes, and macrophage accumulation in inflamed areas antagonises histamine release and subsequent scar tissue formation that may result due to the inflammatory condition.
Manufacturer Information
We currently offer the brand Locoid from New Zealand by Astellas Pharma and from the United Kingdom manufactured by Leo in the strength of 0.1 %/30 gm and 0.1 %/100 gm cream. The generic version is not available.
Get medical help immediately if you have any of these signs of an allergic reaction while taking Locoid. The most common side effects of Locoid may include:
• Acne formation;
• Changes in skin colour;
• Easy bruising;
• Peeling of the skin;
• Skin atrophy;
• Stretch marks
Contact your doctor right away if you have any of the serious side effects, including:
• Blistering of the skin;
• Severe acne;
• Severe stretch marks;
• Unintended weight gain;
• Worsening of the symptoms
You should not take Locoid if you are allergic to Hydrocortisone or have an infected skin condition. Locoid Lipocream should be applied on the skin only. You should use it according to your prescription label, usually 2-3 times daily. Apply a small amount of the cream to the affected area. Do not use a Steroid cream for a long time. Using beyond your doctor’s prescription may worsen and bleach your skin. You should wash your hands before and after applying the cream. Do not apply it to the infected areas of the skin. You should not cover the treated areas with a bandage or heavy clothes. Hydrocortisone may increase your blood sugar. Talk to your doctor if you have diabetes. Talk to your doctor if there is no improvement in your condition despite regular use for seven days.
Before you start taking this medication, tell your doctor about your medical history, especially if you:
• Are breastfeeding or plan to breastfeed;
• Are pregnant or plan to become pregnant;
• Have adrenal gland disorders;
• Have diabetes mellitus;
• Have eye problems;
• Have liver problems;
• Have lung or breathing problems;
• Have severe skin conditions such as infected areas on the skin
Tell your doctor immediately if you become pregnant or think you may be pregnant. During pregnancy, this medication should be used only when needed. It should not be used for long periods or in large amounts. Discuss the risks and benefits with your doctor. It is not known if this medication passes into breast milk. Consult your doctor before breastfeeding. You should use it with caution when using Locoid cream on children. Tell your doctor about all your medications, including prescription, OTC, herbal supplements, and vitamins. There may be a drug interaction between Hydrocortisone and other medications, such as other corticosteroid creams and immunosuppressants. You should keep your medicine secure and away from children’s reach.
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