Clinoril (Sulindac) is a prescription medication used to treat symptoms of arthritis, including pain, swelling, and joint stiffness. The drug treats spinal arthritis, gouty arthritis, shoulder bursitis, rheumatoid arthritis, ankylosing spondylitis, and osteoarthritis. Arthritis is the swelling or inflammation of one or more joints. The disease is autoimmune and can be inherited genetically. Age, sex, and obesity are risk factors for arthritis. The active ingredient in Clinoril is Sulindac. Sulindac belongs to a class of medications called non-steroidal anti-inflammatory drugs (NSAIDs). It works by reducing the body’s production of prostaglandins to decrease swelling, pain, or fever.

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Get medical help immediately if you have any of these signs or an allergic reaction while taking Clinoril. The most common side effects of Clinoril may include the following:
• Acid stomach;
• Belching;
• Constipation;
• Headache;
• Heartburn;
• Nausea;
• Passing gas;
• Skin rash

Contact your doctor right away if you have any of the serious side effects, including:
• Hearing loss;
• Indigestion;
• Severe upper stomach pain with a sick feeling;
• Skin reactions including rash, blisters, or red patches;
• Skin sensitivity to sunlight;
• Unexplained ringing or noise in the ears;
• Unusual tiredness;
• Yellowing skin or eyes

These are not all of the side effects of Sulindac. Always contact your doctor if you notice any unusual symptoms.

You should not take Clinoril if you are allergic to Sulindac or any ingredient in Clinoril. Before you start taking this medication, tell your doctors about your medical history, especially if you:
• Are breastfeeding or plan to breastfeed;
• Are pregnant or plan to become pregnant;
• Have a history of breathing difficulties or high blood pressure;
• Have had asthma;
• Have had bleeding problems;
• Have intolerance to some sugars such as lactose;
• Have problems with your stomach or bowel;
• Have severe heart failure;
• Have severe kidney or liver problems;
• Have stomach or gut ulcer

Tell your doctor about all your medications, including prescription, OTC, herbal supplements, and vitamins. There may be drug interactions between Clinoril and other medicines, including warfarin, fluoxetine, digoxin, prednisolone, cyclosporine, and mifepristone. Do not give Sulindac to children. Tell your doctor immediately if you become pregnant or think you may be pregnant. During pregnancy, you should not use Clinoril in the last trimester. The drug can affect the growth of the fetus and also affect labour. If you are trying to become pregnant, Sulindac may make it more difficult. Clinoril passes into breast milk in small amounts. Do not breastfeed while using this drug. Take Clinoril precisely as prescribed by your doctor. Swallow the tablets whole with water with or after food. Do not stop taking Sulindac without talking to your doctor, even if you feel better. If you miss a dose, take it as soon as you remember, except it is almost time for your next dose. Do not take a double dose to make up for a forgotten dose. Keep Clinoril away from the reach and sight of children. Store below 250C. Store the drug in its original package to protect it from light and moisture.

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