Cibinqo (Abrocitinib) is a prescription medication used to treat moderate-to-severe atopic dermatitis (eczema) in adults and adolescents 12 years and older who are candidates for systemic therapy. Atopic eczema is a common skin condition that causes patches of skin that are itchy, cracked, and sore caused by dry skin and the inability of the skin to retain moisture. This dryness may make the skin more likely to react to certain triggers, causing it to become itchy and sore. The active substance in Cibinqo is Abrocitinib. Abrocitinib belongs to the group of medicine called Dermatologics, Janus kinase inhibitors (JAK). It works by blocking the action of enzymes known as Janus kinases. These enzymes play an essential role in the process of inflammation that occurs in atopic dermatitis. Therefore, Abrocitinib helps to reduce the itching and inflammation of the skin that usually occurs with eczema.
Manufacturer Information
We currently offer the brand Cibinqo from Canada manufactured by Pfizer in the strength of 50 mg, 100 mg, and 200 mg tablets. The generic version is not available.
Get medical help immediately if you have any signs of an allergic reaction while taking Cibinqo. The most common side effects of Cibinqo may include:
• Dizziness;
• Headache;
• Nausea and vomiting;
• Stomach pain;
• Tiredness;
• Urinary tract infection
Contact your doctor right away if you have any of the serious side effects including:
• Breaking out in the cold;
• Burning sensation when you urinate or urinating more often than usual;
• Chest pain that lasts for more than a few minutes or that goes away and comes back;
• Severe tightness, pain, pressure, or heaviness in your chest, throat, neck, or jaw;
• Slurred speech;
• Shortness of breath with or without chest discomfort;
• Weakness in one part or on one side of your body
Before taking the Cibinqo tablet, you should tell your doctor or pharmacist if you are allergic to Cibinqo or its active constituent. It would be best to follow your doctor's instructions on using Cibinqo. It would be best if you use the Cibinqo tablet as prescribed. Cibinqo comes as a tablet and may be taken with or without food. You should swallow the tablet whole with a cup of water, do not crush or chew the Cibinqo tablet. Cibinqo may lower your immune system. If you develop a serious opportunistic infection, you should stop taking the medication until the condition is controlled. You should inform your doctor if your symptoms do not improve after 24 weeks of treatment.
Before you start taking this medication, tell your doctor about your medical history, especially if you:
• Bacterial, viral (including herpes zoster), and other infections due to opportunistic pathogens;
• Heart attack, hypertension, or stroke;
• Kidney disease;
• Liver disease (including viral hepatitis B and C infection);
• Recurrent infection or ongoing infection;
• Tuberculosis
Inform your doctor if you are pregnant or plan to get pregnant while using the Cibinqo table. It may affect female fertility. It would be best to discuss the risks and benefits of using Cibinqo with your doctor. It is unknown if this medication passes into breast milk. Talk to your doctor before breastfeeding your child. Tell your doctor about all your medicines, including prescription, OTC, herbal supplements, and vitamins. There may be a drug interaction between Abrocitinib and other medications such as aspirin, cilostazol, cilostazol, ticlopidine, tirofiban, clopidogrel and anagrelide. Store Cibinqo tablets at room temperature, 68°F to 77°F (20°C to 25°C). Keep it away from the reach of children.