Twynsta (Telmisartan/Amlodipine) is a prescription medication used to treat adults with mild to moderate high blood pressure. If left untreated, high blood pressure can lead to heart attacks, strokes, and kidney problems. It is used to control high blood pressure when an individual medication cannot control the condition. The active ingredients in Twynsta are Telmisartan and Amlodipine. Telmisartan belongs to a class of drugs called angiotensin receptor blockers (ARB). It works by preventing the narrowing of the blood vessels to lower blood pressure and improves blood flow. Amlodipine belongs to a class of drugs called calcium channel blockers. It works by widening the blood vessels to improve blood flow. Treating high blood pressure prevents heart diseases, stroke and kidney failure.
Manufacturer Information
We currently offer the brand Twynsta from Canada manufactured by Boehringer Ingelheim in the strength of 40mg/5mg, 40mg/10mg, 80mg/5mg, and 80mg/10mg tablets. The generic Telmisartan/Amlodipine comes from India also called Cresarr AM by Cipla in the strength of 40mg/5mg and 80mg/5mg tablets.
Get medical help immediately if you have any of these signs or an allergic reaction while taking Twynsta. The most common side effects of Twynsta may include the following:
• Diarrhea;
• Dizziness;
• Fast or pounding heartbeat;
• Flushing;
• Nausea;
• Stomach pain;
• Swelling of hands or feet
Contact your doctor right away if you have any of the severe side effects, including:
• Light-headedness;
• Muscle stiffness;
• New or worsening chest pain;
• Shortness of breath;
• Slow or unusual heart rate;
• Tremors;
• Weakness
These are not all of the side effects of Twynsta. Always contact your doctor if you notice any unusual symptoms.
You should not take Twynsta if you are allergic to Telmisartan, Amlodipine, or any ingredient in Twynsta. Before you start using this medication, tell your doctor about your medical history, especially if you:
• Are 65 years or older;
• Are at risk of developing hyperkalemia;
• Are breastfeeding or planning to breastfeed;
• Are on a low-salt diet;
• Are on dialysis;
• Are pregnant or planning to be pregnant;
• Are taking diabetes medication containing aliskiren;
• Have angina;
• Have been diagnosed with hereditary fructose intolerance;
• Have kidney disease;
• Have liver disease;
• Have low-level of potassium or magnesium in your blood;
• Have primary aldosteronism
Tell your doctor about all your medications, including prescription, OTC, herbal supplements, and vitamins. There may be drug interactions between Twynsta and other medicines, including NSAIDs, diuretics, potassium supplements, ACE inhibitors, medications used to prevent organ transplant rejection, etc. Avoid lithium, digoxin, ketoconazole, St. John's wort, dantrolene, phenytoin, or sildenafil with Twynsta. Tell your doctor if you are pregnant or planning to become pregnant. Do not use Twynsta during pregnancy. The drug may cause injury or death to the fetus, especially when taken in the second or third trimester. Use effective contraception to prevent pregnancy. Inform your doctor if you are breastfeeding or planning to breastfeed. Amlodipine passes into breast milk and may harm a nursing baby. Take Twynsta precisely as prescribed by your doctor. Swallow the tablets whole with water. You may take the drug with or without food. Continue taking the drug even if you feel better. High blood pressure often has no symptoms. You may need to use medication for the rest of your life. Twynsta is not a cure for blood pressure. It helps to control it. Twynsta may make your sleepy or drowsy. Inform your doctor that you are taking Twynsta before undergoing surgery. You may experience a sudden fall in blood pressure when you are under general anesthesia. This drug increases your skin's sensitivity to the sun. Limit exposure to the sun and always use sunscreen SPF-30 or higher. Do not drive or operate machinery until you know how this drug affects you. Avoid alcohol while taking Twynsta. Alcohol can increase the side effects of this drug. Store at room temperature, away from moisture and heat.
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