Rowasa Enema (Mesalamine) is a prescription medication used to treat ulcerative colitis, proctitis, and proctosigmoiditis, as well as other diseases of the colon and inflammatory diseases. Rowasa Enema belongs to a class of medications called 5-aminosalicylates, and works by targeting prostaglandins. Prostaglandins are produced by the enzymes, cyclooxygenase and lipoxygenase. These enzymes are over-active in individuals with inflammatory bowel diseases. Rowasa Enema works by blocking the activity of cyclooxygenase and lipoxygenase, reducing the production of prostaglandins. Reduced production of prostaglandins decreases inflammation in the colon and reduces the symptoms associated with several conditions.
Manufacturer Information
Canadian Pharmacy King currently offers the brand Rowasa Enema also called Salofalk Enema manufactured by Aptalis Pharma and Pentasa Enema manufactured by Ferring in the strength of 1 gm/100 ml, 2 gm/60 ml, 4 gm/100 ml, and 4 gm/60 ml, 7 units per box. The generic version is not available.
Common side effects of Rowasa Enema may include dizziness, rectal pain, colitis, rash, or acne.
Contact your doctor immediately if you notice more serious side effects such as:
• Fever, headache, general ill feeling;
• Rash, itching, eye redness;
• Severe stomach pain, cramping, bloody diarrhea;
• Signs of a kidney stone (severe pain in your side and back, frequent need to urinate, foul-smelling urine, dark or cloudy urine);
• Signs of kidney problems (increased or decreased urination, swelling, weight gain);
• Signs of low white blood cell counts (fever, chills, mouth sores, skin sores, sore throat, cough, feeling light-headed, trouble breathing)
This is not a complete list of side effects. If you notice any other side effects not listed here, please contact your doctor or pharmacist.
You should not use Rowasa Enema if you are allergic to mesalamine, aspirin, sulfasalazine, or salicylates. To make sure Rowasa Enema is safe for you, tell your doctor if you have ever had a skin condition such as eczema, a kidney stone or kidney disease, asthma or sulfite allergy, or liver disease. It is not known if this medication will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant while using this medication. Rowasa Enema is not expected to harm a nursing baby. If you are breastfeeding, tell your doctor if you notice diarrhea in the nursing baby. Avoid getting this medication on clothing, flooring, painted surfaces, vinyl, marble, granite, and other surfaces. This medication may stain surfaces. If you have a skin condition such as eczema, Rowasa Enema could make you sunburn more easily. Avoid sunlight or tanning beds. Wear protective clothing and use sunscreen when you are outdoors. Rowasa Enema may interact with several medications, especially medications for cancer, osteoporosis, infections, organ transplant rejection, bowel disorders, high blood pressure, or pain or arthritis, as well as azathioprine and 6-mercaptopurine. This is not a complete list of interactions, and others may occur. Tell your doctor about any medications, vitamins, or herbal supplements you are currently taking or have recently taken in order to reduce the risk of any possible interactions. Rowasa Enema is not approved for use in children under the age of 12.
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