Promacta (Eltrombopag Olamine) is a prescription medication used to treat low platelet levels in people with a blood disorder called chronic immune thrombocytopenia (ITP) and who cannot be treated with other treatments like medications or surgery to remove the spleen. ITP is an ongoing condition that may cause unusual bruising or bleeding due to an abnormally low number of platelets in the blood. The drug is also used to increase the number of platelets in people who have hepatitis C so that they can begin and continue treatment with interferon and ribavirin. The drug may also be used to treat people with aplastic anemia, a particular blood disorder where the body does not make enough new blood cells. The active ingredient in Promacta is Eltrombopag Olamine. Eltrombopag belongs to a class of drugs caked thrombopoietin receptor antagonists. It works by causing the cells in the bone marrow to produce more platelets.
Manufacturer Information
We currently offer the brand Promacta also known as Revolade from Canada manufactured by Novartis and from India manufactured by GSK in the strength of 25mg and 50mg tablets only. The generic Eltrombopag Olamine is not available.
Get medical help immediately if you have any of these signs or an allergic reaction while using Promacta. The most common side effects of Promacta may include the following:
• Anemia;
• Bruising or bleeding during or after treatment with Promacta;
• Confusion;
• Dark urine;
• Eye pain;
• Jaundice;
• Light-headedness;
• Pain or burning when you urinate;
• Pale skin;
• Shortness of breath;
• Tiredness;
• Vision changes
Contact your doctor right away if you have any of the severe side effects, including:
• Chest pain;
• Coughing up blood;
• Diarrhea;
• Dizziness;
• Severe headache;
• Severe stomach pain;
• Sudden cough;
• Sudden numbness or weakness;
• Swelling or warmth in one leg;
• Vomiting
These are not all of the side effects of Promacta. Always contact your doctor if you notice any unusual symptoms.
You should not take Promacta if you are allergic to Eltrombopag or any ingredient in Promacta. Before you start using this medication, tell your doctors about your medical history, especially if you:
• Are breastfeeding or plan to breastfeed;
• Are of East or Southeast Asian descent;
• Are pregnant or plan to become pregnant;
• Have bleeding problems;
• Have blood cancer;
• Have blood clots;
• Have cataracts;
• Have had surgery to remove your spleen;
• Have liver disease
Tell your doctor about all your medications, including prescription, OTC, herbal supplements, and vitamins. There may be drug interactions between Promacta and other medicines, including antacids and vitamin or mineral supplements that contain magnesium, aluminum, or zinc. Avoid warfarin, ticlopidine, pravastatin, or Fluvastatin with Promacta. Tell your doctor if you are pregnant or planning to become pregnant. Eltrombopag may harm an unborn baby. Use effective birth control while using Promacta and for at least seven days after your last dose. It is not known if Promacta is excreted in breast milk. You should not breastfeed while using this medicine. Inform your doctor if you are breastfeeding or planning to breastfeed. Use Promacta precisely as prescribed by your doctor. You may take the drug on an empty stomach at least one hour before or two hours after eating. If your meal contains fewer than 50mg of calcium, you can take Promacta with your meal. If your food is high in calcium (dairy products, certain fruits, vegetables, or calcium-fortified juices), take the drug at least 2 hours before and 4 hours after eating. Swallow the tablet whole. Do not crush, chew, or break it. Promacta is usually taken for six months. It may take up to 4 weeks before the drug prevents major bleeding episodes. Do not stop taking the drug without informing your doctor. After you stop taking this medicine, your risk of bleeding may be higher than before you started treatment. Be extra careful to avoid cuts or injury for at least four weeks after you stop taking this medicine. Keep Promacta tablets in its original container. Store at room temperature, away from moisture and heat.
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