Linzess (Linaclotide) is a prescription medication that is used to treat irritable bowel syndrome with constipation (IBS-C) and chronic idiopathic constipation (CIC) in adults. This medication works by increasing fluid in your intestines and helps speed up movement of food through the gut. Linaclotide may improve stool texture and lessen symptoms such as bloating, abdominal pain/discomfort, straining, and feelings of incomplete bowel movements.
In a study (Linaclotide for irritable bowel syndrome with constipation - Nov 2012), William D Chey, found that " Linaclotide 290 µg once daily significantly improved abdominal and bowel symptoms associated with IBS-C over 26 weeks of treatment.".
In another study (Low-Dose Linaclotide (72?µg) for Chronic Idiopathic Constipation - August 22, 2017), Philip Schoenfeld, MD, Once-daily linaclotide 72?µg significantly improved CIC symptoms in both men and women with a low rate of discontinuation due to diarrhea over 12 weeks of treatment.".
Manufacturer Information
We currently have the brand Linzess which is also called Constella. Linzess is available in three dosage strengths:
• 72 mcg, 145 mcg capsules - to treat CIC (chronic idiopathic constipation)
• 290 mcg capsules - to treat IBS-C (irritable bowel syndrome with constipation)
Brand Linzess is manufactured by Allergan in Canada (72 mcg, 145 mcg and 290 mcg) or Almirall in the United Kingdom (290 mcg). Generic version of Linzess is currently not available.
The common side effects of Linzess may include bloating, diarrhea or full feeling in your stomach, gas and stomach pain. Stop taking LINZESS and call your doctor right away if you experience severe diarrhea and other serious side effects such as:
• Black, bloody, or tarry stools;
• Leg cramps, or muscle weakness;
• Mood changes, or confusion;
• Severe stomach pain
Before you start taking Linzess, inform your doctor if you are allergic to Linaclotide or if you have any other allergies. Linzess should not be used by children younger than 2 years due to the risk of serious dehydration. Talk to your doctor for details. Avoid use of Linzess in patients 6 years to less than 18 years of age. Avoid drinking alcohol while taking Linzess. You should inform your doctor about your medical history, especially if you have stomach/intestinal blockage. There may be an interaction with Linaclotide, including prescription, over-the-counter, vitamin, and herbal products, talk to your doctor if you are taking any medications, especially anticholinergic drugs. Linzess should not be used during pregnancy or breastfeeding unless the benefit outweighs the risk. Consult your doctor if you are pregnant or breastfeeding.
* Where can I buy Linzess?
You can buy Linzess online from www.CanadianPharmacyKing.com, or by phone, by fax, by mail or email.
* How much does Linzess cost?
Our Canada Pharmacy offers the lowest price for Linzess 290 mcg 84 tablets from the United Kingdom at $351.99. The cost may vary depend on the dosage, quantities, and countries of suppliers.
* Is Linzess covered by insurance?
Unfortunately, we do not accept any insurance.
* Are there any alternative medications to Linzess?
Other alternative medications to Linzess may include: Resolor, Miralax, and Trulance. Consult your doctor first if you make a switch to other prescription medications.