Atropine (Atropine Sulfate) is a prescription injection used to treat slow heart rate (bradycardia) and also helps to restore normal heartbeat in cardiac arrest. Atropine injection can be given minutes before anaesthesia to decrease mucus secretions, such as saliva and other airway secretions. Atropine sulfate monohydrate also works as an antidote in certain types of poisoning and reverses the side effects of certain muscle-relaxing medicines. The active substance in Atropine injection is Atropine Sulfate. Atropine Sulfate belongs to the class of medication called an antimuscarinic agent. It works by blocking the action of acetylcholine at parasympathetic sites in secretory glands. As a result, Atropine inhibits salivation, tracheobronchial secretions, bradycardia, and hypotension.
Manufacturer Information
We currently offer the brand Atropine from Canada manufactured by Sandoz and Teligent Canada Inc. in the strength of 0.4 mg/ml and 0.6 mg/ml ampules injection. Unfortunately, the generic version is not available.
Get medical help immediately if you have any of these signs of an allergic reaction while taking Atropine. The most common side effects of Atropine may include:
• Ataxia;
• Blurred vision;
• Fever;
• Delay gastric emptying;
• Dry mouth;
• Headache;
• Insomnia;
• Palpitation
Contact your doctor right away if you have any of the serious side effects, including:
• Difficulty with urination or bladder outlet obstruction;
• Mood and mental changes;
• Palpitation and feeling of irregular heartbeat;
• Rash and facial swelling;
• Urinary incontinence;
• Worsening of symptoms
You should not take Atropine if you are allergic to Atropine sulfate. Before you start taking this medication, tell your doctor about your medical history, especially if you:
• Are breastfeeding or plan to breastfeed;
• Have eye problems such as glaucoma;
• Are pregnant or plan to become pregnant;
• Have problems with your heartbeat;
• Have intestinal obstruction;
• Have lung or breathing problems;
• Have overactive thyroid;
• Have urinary retention or difficulty with passing urine;
Atropine injection is given into the veins (intravenous injection) or muscles (intramuscular injection) in a hospital setting under the supervision of a doctor. You should not administer an Atropine injection without checking with your doctor or pharmacist. It may cause blurred vision. Do not drive or do anything that requires full attention until you know how this medicine affects you. Avoid taking Atropine Sulphate Injections if you have urinary retention, high blood pressure, heart problems, or high thyroid hormone levels. Tell your doctor immediately if you become pregnant or think you may be pregnant. Your doctor will decide what dose and how often you receive Atropine Injections. You should discuss with your doctor if there is no improvement in your condition or if you experience a severe side effect. Atropine Sulphate Injection may be unsafe to use during pregnancy as it readily crosses the placental barrier. Your doctor will discuss the risk and benefits of using Atropine with you. Atropine does not pass into breast milk; hence it is safe for nursing mothers to receive the injection. Tell your doctor about all your medications, including prescription, OTC, herbal supplements, and vitamins. There may be a drug interaction between Atropine Sulfate and other medications such as warfarin, quinidine, metoclopramide, pilocarpine.
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