Apresoline (Hydralazine) is a prescription medication used to lower high blood pressure (hypertension) or severe hypertensive conditions requiring immediate intervention, such as pre-eclampsia, eclampsia, hypertensive emergency, or deteriorating heart failure. The active ingredient in Apresoline is Hydralazine. Hydralazine belongs to the class of medication called vasodilators. It works by relaxing the blood vessels and allowing blood to flow easily to and away from the heart. As a result, lowering high blood pressure prevents strokes, vision loss, kidney failure, and sudden cardiac death.

Manufacturer Information

Get medical help immediately if you have signs of an allergic reaction while taking Apresoline. The most common side effects of Apresoline may include:
• Chest pain;
• Diarrhea;
• Headache;
• Nausea and vomiting;
• Palpitations;
• The sudden drop in blood pressure

Contact your doctor right away if you have any of the severe side effects, including:
• Change in mental status (psychotic behavior);
• Feeling dizzy or syncopal attacks;
• Peripheral neuropathy or tingling sensation;
• Severe headache that doesn’t go away;
• Severe muscle and bone pain

Before using a Hydralazine tablet, tell your doctor or pharmacist if you are allergic to Hydralazine, aspirin, tartrazine, or any ingredient in hydralazine tablets. You should use your medication according to your prescription label. Apresoline is a tablet and should be taken orally with a cup of water. Your dose depends on the nature of your blood pressure reading and response to treatment. Your doctor may start you on a low dose and watch your blood pressure as time passes. You should not increase your dose at any time as this may cause a sudden drop in your blood pressure and may cause profound side effects. People with high blood pressure may not experience any symptoms at all. Treating hypertension is a lifelong treatment option, do not stop using your medication at any time. It may take severe days before you see the changes in your blood pressure due to Hydralazine medication. You should check your blood pressure regularly. Contact your doctor if there are no changes in your blood pressure or if your condition worsens (increasing blood pressure readings).

Before you start taking this medication, tell your doctor about your medical history, especially if you:
• Are breastfeeding or plan to breastfeed;
• Are pregnant or plan to become pregnant;
• Have had episodes of depression or seizures;
• Have problems with your heartbeat;
• Have liver problem;
• Have lung or breathing problems;
• Have rheumatoid arthritis

Tell your doctor immediately if you become pregnant or think you may be pregnant. During pregnancy, Hydralazine can regulate high blood pressure in women with pre-eclampsia or pregnancy-induced hypertension under the supervision of a medical doctor. You should use Hydralazine cautiously to prevent a rapid drop in blood pressure. Hydralazine passes into human breast milk. Discuss the risk and benefits of using this medication with your doctor before breastfeeding your child. Tell your doctor about all your medicines, including prescription, OTC, herbal supplements, and vitamins. There may be a drug interaction between Hydralazine and other medications such as aspirin, warfarin, carbidopa, bisoprolol, nifedipine, and tadalafil. You should store Hydralazine tablets in the container it came in, tightly closed and out of reach of children.

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